Insulin and IGF1 enhance IL-17-induced chemokine expression through a GSK3B-dependent mechanism: a new target for melatonin's anti-inflammatory action
نویسندگان
چکیده
منابع مشابه
IL-17 enhances chemokine gene expression through mRNA stabilization.
IL-17 plays an important role in host defense and autoimmunity via the induction of proinflammatory gene expression, particularly in combination with TNF-alpha. The molecular mechanisms by which IL-17 regulates such expression are not well understood. Using the mouse chemokine CXCL1 (KC) gene as a model, we have examined the effects of IL-17 alone or in combination with TNF-alpha on transcripti...
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Candida is the third most common cause of bloodstream infections in hospitalized patients. Immunity to C. albicans, the most frequent species to be isolated in candidiasis, involves a well-characterized Dectin-1/caspase-associated recruitment domain adaptor 9 (CARD9)/IL-17 signaling axis. Infections caused by non-albicans Candida species are on the rise, but surprisingly little is known about i...
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جنبه های گوناگونی از زندگی در ایران را از جمله سبک زندگی، علم و امکانات فنی و تکنولوژیکی می توان کم یا بیش وارداتی در نظر گرفت. زبان انگلیسی و روش تدریس آن نیز از این قاعده مثتسنی نیست. با این حال گاهی سوال پیش می آید که آیا یک روش خاص با زیر ساخت های نظری، فرهنگی اجتماعی و آموزشی جامعه ایرانی سازگاری دارد یا خیر. این تحقیق بر اساس روش های ترکیبی انجام شده است.پرسش نامه ای نیز برای زبان آموزان ...
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ژورنال
عنوان ژورنال: Journal of Pineal Research
سال: 2013
ISSN: 0742-3098
DOI: 10.1111/jpi.12084